Monthly Archives: October 2017

Overview: Soft Tissue Sarcoma

Soft tissue sarcoma is a cancer that starts in soft tissues of the body, including muscle, tendons, fat, lymph vessels, blood vessels, nerves, and tissue around joints. The tumors can be found anywhere in the body but often form in the arms, legs, chest, or abdomen. Signs of soft tissue sarcoma include a lump or…

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In vivo Matrigel Plug Angiogenesis Assay

The matrigel plug angiogenesis assay is a simple in vivo technique to detect the newly formed blood vessels in the transplanted gel plugs in nude mice. The matrigel matrix is derived from the engelbroth-holm-swarm (EHS) mouse sarcoma, and its composition is comparable to the basement membrane proteins. The matrigel can induce differentiation of a variety of cell…

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Gene Regulation (Videos)

Examples of Gene Regulation Gene Regulation Inducer Gene Regulation Is Important Why Gene Regulation Promoter Operator Gene Regulation Transcriptional Dynamics Identify common microRNA binding sites present in a list of down-regulated genes Identify five genes that activate EGFR using Ingenuity IPA Identify five genes that inhibit EGFR using Ingenuity IPA Identify microRNA target genes Identify…

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TCGA study of liver cancer reveals potential targets for therapy

A comprehensive analysis of hepatocellular carcinoma (HCC), the most common type of liver cancer, has revealed several genomic changes that may represent new therapeutic targets. The incidence of HCC has risen over the last 20 years and currently has a poor 5-year overall survival rate of approximately 15 percent. There are several known risk factors…

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